Your 2025 Guide to Creating More Effective B2B Email Marketing Campaigns
How to craft compelling content, segment audiences, and improve your open and conversion rates
How useful is B2B email marketing in the year 2025? Pretty useful. Apps, trends, and tools may come and go, and email marketing remains one of the best investments when it comes to building relationships with your customers and engaging prospective business partners. And for those who have limited budgets to work with, email marketing can be implemented with relatively low overhead costs, making it a great way to get the most for your money.
According to a report by McKinsey & Company:
E-mail remains a significantly more effective way to acquire customers than social media—nearly 40 times that of Facebook and Twitter combined (exhibit). That’s because 91 percent of all US consumers still use e-mail daily, and the rate at which e-mails prompt purchases is not only estimated to be at least three times that of social media, but the average order value is also 17 percent higher.
That covers why you should invest in B2B email marketing, but now comes the follow-up question: How? How do you craft a campaign that gets the clicks, the open rates, and the return on investment you need?
Let’s Start With Content Strategies
A whole section just for content? It’s that important?
Yes. If you don’t deliver on the content side of things, all the tricks, tools, and segmentations in the world aren’t going to see your email marketing stats improve. So let’s start with our foundations.
1. Choose quality over quantity.
Churning out emails just for the sake of getting into your clients and prospective customers’ inboxes is going to result in you getting relegated to the spam folder. Each email you send out to businesses should have a point and intent behind it; provide value to recipients; and vary in what it’s trying to deliver, whether that’s an article or essay, video, photo, news, or some other type of information.

2. Hook them with the subject line.
This one is really pivotal. Subject lines can make or break your email campaign because they’re the only part of your content that your list is guaranteed to see. Whether they click-thru and engage with your email hinges on if the subject line is enough of a draw. Focus on subject lines that:
- Create urgency — e.g., limited time, act now, ends today
- Drive curiosity — e.g., discover the secret, the key to success you’re missing
- Offer value — e.g., exclusive insights, boost your ROI, proven strategies, complementary demo
3. Your customers are unique; your content should be, too.
A successful B2B email marketing campaign doesn’t utilize cookie-cutter content. Instead, it takes a look at your pool of clients and prospective customers and breaks them down into personas — groups based on things like location, industry, and interests. Once you have those personas, you gear your content specifically to them so that your emails have a better chance of resonating with their needs.
4. Offer them real value.
With B2B marketing in particular, it’s important to establish that you have valuable information and insights to share about your field. Don’t just continue to pitch your business over and over again. Show what you have to offer them by engaging with current topics and trends in your industry.
5. Don’t forget a clear call to action.
Seems like an obvious one, but you’d be surprised how often it can get lost in the shuffle. Each email you send out should have a CTA that aligns with your goals for it and ensure that it is concise, direct, and easy to spot.
Want to stay up to date with the news and resources from EdwardsSchoen?
Sign up for our monthly newsletter to stay in the know!
Okay, What Other Strategies and Best Practices Are Out There?
There are a lot of other key components to a successful B2B email marketing campaign that directly impact whether you’re reaching the right people at the right time. Some of these are steps you should take before anyone sits down to write content and some are backend and post-campaign tactics designed to help you in the long-term.

1. Outline your personas and segmentation.
This is one of those pre-content steps. Segmenting your email list and developing personas for each group will help you craft unique messaging that can greatly improve your positive interactions. Intuit Mailchimp ran the stats on the effects of email segmentation and discovered that segmented campaigns performed “markedly better”:
- Open rates were 14.31% higher
- Unique open rates were 10.64% higher
- Clicks were 100.95% higher
- Unsubscribe requests were 9.37% lower
2. Make it personalized.
We’ve talked on here before about personalization; it’s not just a fun trick anymore. It’s more often than not a customer expectation. Campaign Monitor found that emails that had personalized subject lines that addressed the recipient by name were 26% more likely to be opened. So if you’re already implementing segmentation and personas and then add personalization on top of that, you take your B2B email marketing campaign from meaningless spam to a uniquely tailored message.
3. Prioritize your goals for each email.
We mentioned this above in the content section: every email you send should have a purpose behind it. But to get the best results, it can’t be vague. Your goals should be actionable and measurable. Your key performance indicators should be clear to everyone involved. That way you can tailor your call to action and more confidently assess whether the campaign is working as intended.
4. Test, change it up, test again.
If you don’t make time to try new ideas or strategies, dabble in different content, compare the performance of subject lines, then your email marketing campaign is likely to stagnate at a certain point. Experimenting with templates, content types, calls to action, and subject lines can lead to results and avenues you may not have thought of before.
5. Create a calendar and campaign flow.
This links up with point #3 above and is another step you ought to complete well before you try to get your content down. Because while you’re segmenting and creating personas and figuring out your goals, you should be outlining a calendar and flow for your email marketing campaigns. Decide how often you want to be sending out messages, what time of day is best for them to hit inboxes, how should one message flow into the next, and how many you need in order to see conversions.
6. Stay compliant.
An especially important point in today’s marketing landscape, you need to triple-check that your email list is compliant with new laws on subscribers. The recipients you contact need to have explicitly permitted you to contact them; you’re not allowed to get their information from another provider. So in addition to vetting the email list you already have, you should look into ways to generate more direct contacts. For instance, offering resources or access to related information in exchange for users’ email addresses, creating online spaces where clients can interact, hosting webinars that capture emails as part of registration, etc.
Get B2B Email Marketing Results
It may seem a little wild that in 2025, email marketing is still one of the most reliable means of connecting with your B2B customers and clients, but the statistics don’t lie. When done right, a B2B email marketing campaign can be a low-cost, high-ROI opportunity and one of the best ways to utilize your budget. Just make sure you’re taking the necessary steps to make it count and not get relegated to the dreaded spam folder.